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Literature summary extracted from

  • Di Cerbo, A.; Laurino, C.; Palmieri, B.; Iannitti, T.
    A dietary supplement improves facial photoaging and skin sebum, hydration and tonicity modulating serum fibronectin, neutrophil elastase 2, hyaluronic acid and carbonylated proteins (2015), J. Photochem. Photobiol. B, 144C, 94-103.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.71 collagen fiber + H2O Homo sapiens
-
 ?
-
 ?
3.4.21.71 elastic fiber + H2O Homo sapiens
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.71 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.71 neutrophil
-
 Homo sapiens
-
3.4.21.71 serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.71 collagen fiber + H2O
-
 Homo sapiens ?
-
 ?
3.4.21.71 elastic fiber + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.71 neutrophil elastase 2
-
 Homo sapiens

Expression

EC Number Organism Comment Expression
3.4.21.71 Homo sapiens serum neutrophil elastase 2 concentration is significantly decreased in patients treated with the dietary supplement down
3.4.21.71 Homo sapiens serum elastase 2 concentration was higher in patients affected by photoaging if compared with healthy controls compared with subjects receiving placebo 2 weeks after the end of treatment up

General Information

EC Number General Information Comment Organism
3.4.21.71 physiological function the enzyme's biological functions include involvement in migration of neutrophils by means of focal proteolysis, killing of microorganisms, and degradation/activation of various proteins including cytokines, chemokines and ECM proteins Homo sapiens